Expression of cyclooxygenase-2 in ovarian cancer cell lines.
- Author:
Xiaoyan, LI
;
Weihong, DONG
;
Zehua, WANG
- Publication Type:Journal Article
- MeSH:
Cell Line, Tumor;
Cyclooxygenase 2/genetics;
Cyclooxygenase 2/*metabolism;
Ovarian Neoplasms/*enzymology;
Ovarian Neoplasms/*pathology;
RNA, Messenger/genetics;
RNA, Messenger/metabolism
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2005;25(5):536-7
- CountryChina
- Language:English
-
Abstract:
To investigate the expression of cyclooxygenase-2 (COX-2) in ovarian cancer cell lines, RT-PCR and immunocytochemistry were used to detect the expression of COX-2 in 5 ovarian cancer cell lines. The expression of COX-2 mRNA and protein was detected in all 5 cell lines. It is suggested that COX-2 is expressed in ovarian cancer cell lines, which provides a basis for the chemoprevention of ovarian cancer.
