Lipid management in Diabetes Mellitus: A Singapore Perspective
- Author:
Tan Chee Eng
- Publication Type:Journal Article
- Keywords:
Statins;
Very High Risk;
High Risk;
Macrovascular Complications
- From:The Singapore Family Physician
2017;43(1):7-9
- CountrySingapore
- Language:English
-
Abstract:
Patients with Diabetes Mellitus (DM) have increased risk of atherosclerosis and up to half die during the first myocardial infarction. Primary prevention of cardiovascular disease (CVD) should be a major goal in the management of DM patients. DM patients with the highest risk (established CVD or chronic kidney disease) should have aggressive lipid-lowering therapy. Statin therapy should be the first line of therapy for all DM patients with elevated LDL-C. Ezetimibe can be added if LDL-C target is not reached at maximally tolerated statin dose. Fibrates can be used in DM patients with TG of >4.5 mmol/l (400 mg/dl). The adverse effects from lipid-lowering therapy are low while the benefits of intervention are well proven and significant.
