Extending Quadrivalent Human Papilloma Virus (HPV) Vaccination To Males
- Author:
Chan Hian Hui Vincent
- Publication Type:Review
- Keywords:
Quadrivalent HPV Vaccination;
Cancer;
Males;
Prevention
- From:The Singapore Family Physician
2015;41(3):65-73
- CountrySingapore
- Language:English
-
Abstract:
Introduction: Human papilloma virus (HPV)-related genital
warts and cancers can lead to significant morbidity. The
ACIP 2011 from the United States recommends routine
quadrivalent HPV vaccination for both males and females for
primary prevention.1 This study reviews current evidence on
vaccinating males routinely, and determines if it can be
applied to Singapore.
Methods: Relevant articles from PubMed were obtained by
searches using the search words “quadrivalent HPV
vaccination”, “males”, “cancer” and “prevention”. Three
retrieved articles are included in this review and 3 additional articles are included from the references of the selected articles.
Results: Quadrivalent HPV vaccination is effective in the
primary prevention of HPV-related genital warts and cancers
in both genders. Effectiveness in the secondary prevention of HPV-related recurrent high-grade intra-epithelial neoplasia(HGAIN) was suggested in a cohort study among men. The vaccine is safe with minor side effects of localised injection site pain.
Conclusion: Given the efficacy and safety of quadrivalent
HPV vaccination in both males and females, local studies
should be done to confirm the benefits of routine vaccination.
