A randomized controlled trial on the efficacy and safety of a modified ready to use therapeutic food among malnourished children.
- Author:
Laylo-Navarro Celestina Raquel B
;
Limos Elizabeth M
;
Martinez Elizabeth G
- Publication Type:Journal Article, Original
- Keywords: 18 Months To 10 Years Old; Energy Dense Food; Food Supplementation; Weight Gain
- MeSH: Human; Male; Female; Child; Child Preschool; Infant; Thinness; Philippines; Weight Gain; Taste; Arm; Weight Loss; Energy Intake; Dietary Supplements; Taste Perception; Malnutrition
- From: Acta Medica Philippina 2011;45(1):29-33
- CountryPhilippines
- Language:English
-
Abstract:
RATIONALE: In the Philippines, 25% of children < 10 years old are underweight. The use of energy-dense ready-to-use therapeutic food (RUTF) augments caloric intake. No local studies have evaluated RUTF.
OBJECTIVE: To determine the efficacy, safety and acceptability of a modified RUTF (mRUTF) to supplement caloric intake.
METHOD: One hundred (100) children 18 months to 10 years old with mild to moderate malnutrition were randomized to either mRUTF or control group. The treatment arm received mRUTF during weekdays for 5 weeks while controls had no supplementation. Anthropometric measurements were taken at baseline, weekly for 5 weeks and 2 weeks post-supplementation.
RESULTS: The two groups were comparable at baseline. At five weekly intervals, there was no significant difference in weight, height and mid upper arm circumference between groups, although the mean percentage weight gain of the mRUTF group was higher compared with controls (8% vs 2.6%, p=0.15). Cessation of supplementation resulted in weight loss in the mRUTF group. [mRUTF: -0.40 (0.33) vs -0.03 (0.35), p=0.00]. The taste of mRUTF was acceptable.
CONCLUSION: Ready-to-use-therapeutic food is an effective, safe and acceptable alternative supplement for children, 18 months to 10 years old, with mild to moderate malnutrition.