Peripheral Vascular Leakage Findings of Asymptomatic Eyes Based on Fluorescein Angiography.
10.3341/jkos.2014.55.7.1017
- Author:
Sang Hyup LEE
1
;
Yong Un SHIN
;
Byung Ro LEE
;
Myung Kyoo KO
Author Information
1. Department of Ophthalmology, Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Korea. stynel@nate.com
- Publication Type:Original Article
- Keywords:
Arm-retinal circulation time;
Fluorescein angiography;
Peripheral leakage;
Venous filling time
- MeSH:
Angiography;
Fluorescein Angiography*;
Hypertension;
Refractive Errors;
Retina;
Retinaldehyde;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
2014;55(7):1017-1023
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report peripheral vascular retinal leakage findings of asymptomatic eyes based on fluorescein angiography, and investigate the associated factors. METHODS: Data were collected retrospectively from 47 subjects (94 eyes) and the peripheral leakage results based on fluorescein angiography were analyzed. The relationship between peripheral leakage findings and other factors including-arm-retinal circulation time (ARCT) and venous filling time (VFT), refractive error, age, hypertension, and diabetes- was evaluated. RESULTS: Ten eyes had peripheral leakage (21.3%). The mean age was 34.7 +/- 7.86 years in the non-leakage group and 44.3 +/- 9.63 years in the leakage group; the difference between the groups was statistically significant (p = 0.001). The mean spherical equivalent was -2.85 +/- 2.71 diopter in the non-leakage group and -3.46 +/- 3.62 diopter in the leakage group; the difference between the groups were not significant (p = 0.471). The mean ARCT was 10.50 +/- 2.06 seconds in the non-leakage group and 11.76 +/- 2.47 seconds in the leakage group; the difference between the groups was statistically significant (p = 0.041). The mean VFT was 9.70 +/- 1.91 seconds in the non-leakage group and 10.75 +/- 1.40 seconds in the leakage group; the difference between the groups was statistically significant (p = 0.048). CONCLUSIONS: Peripheral leakage can be found in asymptomatic eyes. Age, VFT, and ARCT were correlated to peripheral leakage findings based on angiography. These leakage findings were thought to be related with histological properties and physiological changes in peripheral retina.