Long term outcome of type 2 diabetic patients with critical limb ischemia.
- Author:
Tuazon Danny Joseph
;
Plata-Que Ma. Teresa
- Publication Type:Journal Article, Original
- MeSH: Human; Male; Female; Middle Aged; Peripheral Arterial Disease; Kaplan-meier Estimate; Patient Readmission; Amputation; Lower Extremity; Angioplasty; Diabetes Mellitus, Type 2
- From: Philippine Journal of Internal Medicine 2015;53(2):1-5
- CountryPhilippines
- Language:English
-
Abstract:
INTRODUCTION: Diabetes Mellitus is associated with vascular disease. One of its macrovascular complications is peripheral arterial disease (PAD), which can present as critical limb ischemia (CLI) that can eventually lead to amputation and death.
OBJECTIVE: Determine the long-term outcome of Type 2 diabetic patients with critical limb ischemia in National Kidney and Transplant Institute (NKTI).
METHODS: Computerized search of NKTI Medical Records Section was done using the Docuview. Type 2 diabetic patients with critical limb ischemia of the lower extremities were included in the study. Patients were grouped according to the intervention received (No intervention, Bypass Graft or Peripheral Angioplasty). Endpoints such as amputation and mortality were ascertained on readmissions and on outpatient records. Data processing and analyses were performed using SPSS v20. Kaplan-Meier Survival Analysis was used to examine days to amputation and days to mortality between groups.
RESULTS: Twenty-three (23) patients were included in the study. There was no significant difference on the baseline characteristics of those who received revascularization and those who did not have revascularization. Amputation rate was 31% while mortality rate was 30% for the whole population. Patients who had revascularization seemed to have greater probability of amputation and lesser probability of dying, but these were not statistically significant based on Kaplan - Meier Survival Curves p values of 0.918 and 0.433, respectively.
CONCLUSION: Diabetic patients with CLI still carries a high risk of amputation and mortality even with revascularization but the time to amputation is longer for those who were revascularized.