Five cases of cytomegalovirus infection detected by in situ hybridization and antigenemia assay.
10.3346/jkms.1994.9.6.507
- Author:
Jin Hong YOO
1
;
Jong Young CHOI
;
Yang Ree KIM
;
Yeong Jin CHOI
;
Sang In SHIM
;
Hak Ki KIM
;
Chul Woo YANG
;
Yong Soo KIM
;
Chi Wha HAHN
;
Wan Shik SHIN
;
Chong Won PARK
;
Moon Won KANG
;
Choon Choo KIM
;
Byung Kee BANG
;
Dong Jip KIM
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Cytomegalovirus;
Bone Marrow;
Transplantation;
In Situ Hybridization
- MeSH:
Adolescent;
Adult;
Antigens, Viral/*blood;
*Bone Marrow Transplantation;
Case Report;
Cytomegalovirus/*immunology;
Cytomegalovirus Infections/complications/*diagnosis;
Fatal Outcome;
Graft vs Host Disease/complications;
Human;
Immunocompromised Host;
In Situ Hybridization;
Kidney Failure, Chronic/complications;
Kidney Transplantation;
Leukemia/*complications/therapy;
Leukemia, Lymphocytic, Acute, L2/complications/therapy;
Leukemia, Myelocytic, Acute/complications/therapy;
Leukemia, Myeloid, Chronic/complications/therapy;
Male;
Viremia/*diagnosis
- From:Journal of Korean Medical Science
1994;9(6):507-512
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report five cases of cytomegalovirus infection in immunocompromised patients which were detected by either cytomegalovirus antigenemia assay or in situ hybridization. Four cases had leukemia and the other had chronic renal failure. All the three BMT recipients suffered from GvHD. Interestingly, there was an unique case of CMV disease without a history of BMT, which reminded us that CMV could attack immunocompromised patients who had not undergone transplantation, too. Four out of five cases died. We think that cytomegalovirus infection or disease should not be regarded as a minor problem in post-transplantation infection in Korea.
