Androgen insensitivity syndrome (AIS).
- Author:
Iskandar Diana
;
Alensuela Anna Belen I.
- Publication Type:Case report
- MeSH: Human; Female; Adult; Androgen-insensitivity Syndrome; Ar Protein, Human; Receptors, Androgen; Estrogen Replacement Therapy; Phenotype; Infertility, Male; Mutation; Genes, X-linked; Sexual Development; Genitalia
- From: Philippine Journal of Obstetrics and Gynecology 2016;40(2):39-46
- CountryPhilippines
- Language:English
-
Abstract:
Androgen Insensitivity Syndrome (AIS) is a rare condition, it is an X-linked-mutation that is considered as a disease caused by resistance of androgen receptor to its actions. It is expressed in a variety of phenotypes ranging from male infertility to completely normal female external genitalia. This is a case of a 25 year-old with Complete Androgen Insensitivity Syndrome (CAIS), presented as phenotypical female with secondary sexual development, bilateral inguinal masses. Gonadectomy, estrogen replacement therapy and psychological support are part of long term management.