- Author:
Ma. Melizza S. Villalon
1
;
Celso V. Ureta
1
Author Information
- Publication Type:Case Reports
- Keywords: Parathyroid Carcinoma; Primary Hyperparathyroidism
- MeSH: Human; Female; Middle Aged; Parathyroid Neoplasms; Parathyroidectomy; Thyroidectomy; Hypercalcemia; Thyroid Gland; Calcium; Parathyroid Glands; Lithotripsy; Kidney Calculi; Parathyroid Hormone
- From: Philippine Journal of Otolaryngology Head and Neck Surgery 2015;30(1):54-58
- CountryPhilippines
- Language:English
-
Abstract:
OBJECTIVES: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management.
METHODS:
Design: Case Report
Setting: Tertiary Government Hospital
Patient: One
RESULTS: A 54-year-old woman presented with a 3-year history of recurrent nephrolithiasis despite several courses of shock wave lithotripsy. She had persistent hypercalcemia and parathyroid hormone levels were noted to be elevated. Neck ultrasound showed a hypoechoic solid nodule measuring approximately 1.7 x 1.6 cm in the lateral inferoposterior aspect of the left thyroid lobe. Parathyroid scintigraphy revealed a focal uptake on the left lower thyroidal bed. The patient underwent left inferior parathyroidectomy with subtotal thyroidectomy and isthmusectomy Frozen section reported a parathyroid tumor and the final histopathologic results revealed a parathyroid carcinoma.
CONCLUSION: A rare case of parathyroid carcinoma was presented manifesting with recurrent nephrolithiasis. Elevated serum calcium and intact parathyroid hormone (iPTH) can confirm a primary hyperparathyroid problem. Neck ultrasound and parathyroid scintigraphy help in the localization of a parathyroid tumor. Only final histopathologic results can confirm the diagnosis of parathyroid carcinoma. Complete surgical excision is the treatment of choice and offers a good prognosis. - Full text:28 pjohns.pdf