Retinopathy in a patient with systemic lupus erythematosus

Fanz Marie Cruz; Ildefonso Chan; Cherica Tee; Carien Gulay; Leonila Dans; Jennifer Otadoy-agustin; Marysia Recto

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Retinopathy in a patient with systemic lupus erythematosus

Author: Fanz Marie Cruz ¹ ; Ildefonso Chan ¹ ; Cherica Tee ² ; Carien Gulay ² ; Leonila Dans ² ; Jennifer Otadoy-Agustin ³ ; Marysia Recto ³
Author Information

1. Department of Ophthalmology and Visual Sciences, University of the Philippines-Philippine General Hospital Manila, Philippines
2. Section of Rheumatology, Department of Pediatric, University of the Philippines-Philippine General Hospital Manila, Philippines
3. Section of Allergy and Immunology University of the Philippines-Philippine General Hospital Manila, Philippines
Publication Type:Journal Article
MeSH: Lupus Erythematosus; Systemic Retinopathy Of Prematurity Antibodies; Antiphospholipid
From: Philippine Journal of Ophthalmology 2009;34(2):66-69
CountryPhilippines
Language:English
Abstract: Objective:To descibe a case of bilateral severe ischemic retinopathy in a patient with systemic lupus erythematosus (SLE) and elevated antiphospholipid antibody.
Methods:This is a case report.
Results:An otherwise healthy 16-year-old Filipino female presented with bilateral diffuse retinal arteriolar occlusion, wide areas of capillary nonperfusion, and macular ischemia. The diffuse retinal ischemia eventually led to neovascularization and fibroproliferative-membrane formation. Despite laser panretinal photocoagulation, one eye developed vitreous hemorrhage requiring vitrectomy. She was diagnosed to have SLE with mildly elevated anticardiolipin antibody on serial measurements and treated with anticoagulant to prevent further thrombotic episodes.
Conclusion:This form of severe SLE retinopathy associated with elevated levels of antiphospholipid antibodies is rare. When it occurs, recognition is vital so that appropriate treatment can be instituted.
Full text:PJO 127.pdf