Three brothers, aged 5, 19 and 24 years, from Tuguegarao, consulted because of walking difficulty due to stiffening of lower extremities which started at varying ages. Common findings were mild spasticity and weakness in both lower extremities, consistent with Strumpell-Lorrain Syndrome. Individualized rehabilitation medicine interventions were provided to address different functional deficits, leading to improved outcomes. This case series aims to illustrate the importance of initiating early, comprehensive rehabilitation to maximize function and minimize complications.