Fetal chromosomal anomalies during pregnancy
- Author:
Dang Le Dung Hanh
- Publication Type:Journal Article
- Keywords:
Chromosomal anomalies
- MeSH:
Chromosome Disorders;
Pregnancy
- From:Ho Chi Minh city Medical Association
2005;10(4):209-213
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Fetal chromosomal anomalies can be of number or of structure, on autosomal or on sex chromosomes. Prevalence of anomalies was approximately 1/150 of live births. However, some chromosomal anomalies did not show abnormal phenotypes. Abnormality of chromosomes was a main cause of spontaneous abortion and stillbirth, especially early abortion. Most of anomalies happened during gametogenesis of parent having normal chromosomes. The others were inherited by abnormalities from parent who had abnormal genotype but normal phenotype. Chromosomal anomalies are diagnosed by recognizing abnormal chromosome. Diagnosis was recommended when abnormal ultrasound was detected or when there were abnormality in history of mother and family. Chromosomal anomalies increased also with maternal age
