Effects of dexamethasone versus saline-impregnated nasal packing on the postoperative outcome of patients with chronic rhinosinusitis and nasal polyps after endoscopic sinus surgery: A randomized controlled trial.
- Author:
Shella May A. Promentilla
1
;
Rubiliza DC. Onofre
1
;
Benjamin SA. Campomanes, Jr.
1
Author Information
- Publication Type:Journal Article
- Keywords: Nasal Polyp; Intranasal Absorption
- MeSH: Human; Male; Female; Middle Aged; Adult; Young Adult; Adolescent; Dexamethasone; Endoscopy; Nasal Cavity
- From: Philippine Journal of Otolaryngology Head and Neck Surgery 2016;31(1):6-9
- CountryPhilippines
- Language:English
-
Abstract:
OBJECTIVE: To evaluate the effects of Dexamethasone-impregnated absorbable nasal pack versus saline-impregnated nasal packing on postoperative outcome of nasal cavities after endoscopic sinus surgery using the Perioperative Sinus Evaluation Scoring System (POSE) and Lund and Kennedy Endoscopic Scoring System.
METHODS:
Design: Prospective, randomized, double blinded, placebo-controlled trial
Setting: Single Center Tertiary Government Hospital
Participants: Nineteen (19) patients aged 15 years old and above, diagnosed with chronic rhinosinusitis, with nasal polyposis grade 3, who underwent endoscopic sinus surgery from January 2015 to August 2015
RESULTS: Nasal cavities that received postoperative dexamethasone-impregnated nasal packs showed significantly lower POSE scores than placebo on post-op Days 14 (p value 0.0022; 95% CI: -2.113 to -0.5116) as well as lower Lund-Kennedy Scores on post-op day 14 (p value of 0.0180; 95% CI: -2.493 to - 0.2571) and day 28 (p value of 0.007; 95% CI: -1.56275 to -0.2832)
CONCLUSION: Dexamethasone-impregnated absorbable nasal packing affords better postoperative outcomes: less edema, crusting, secretions, and synechiae, than saline-impregnated absorbable packing in later postoperative days.
- Full text:Pjohns 34.pdf
