Papillary thyroid carcinoma identified on bone scan with SPECT/CT in a patient presenting with multiple bone metastases.
- Author:
Barrenechea Angelica A.
;
Goco Gerard L.
;
Bandong Irene S.
- Publication Type:Case Reports
- MeSH: Human; Female; Aged; Thyroid Neoplasms; Thyroid cancer, papillary; Tomography, Emission-Computed, Single-Photon; Low Back Pain
- From: The Philippine Journal of Nuclear Medicine 2015;10(2):44-48
- CountryPhilippines
- Language:English
-
Abstract:
This is a case report of a 65-year-old female with lumbar vertebral lesions secondary to an unknown primary malignancy. 99mTc-methylene diphosphonate bone scintigraphy showed multiple bone metastases as well as focal extraosseous uptake in the area above the right supraclavicular area. Further imaging with SPECT/CT localized the calcified extraosseous uptake to the right thyroid bed. These findings narrowed down the primary malignancy to a thyroidal origin, which was eventually proven as such through immunohistologic studies of the lumbar lesions. Different pathophysiologic mechanisms of extraosseous uptake in bone scintigraphy and how SPECT/CT can increase the diagnostic value of a standard nuclear medicine procedure are highlighted in this paper.