OBJECTIVES: To determine the clinicopathologic characteristics of patients with pre-operative diagnosis of endometrial polyp who underwent hysteroscopy in the Philippine General Hospital and to identify possible risk factors for pre-malignancy and malignancy among patients with pre-operative diagnosis of endometrial polyp.

STUDY DESIGN: Admission logbooks and surgico-pathologic census were analyzed to identify patients with a pre-operative diagnosis of endometrial polyp who underwent hysteroscopy from June 2009 to June 2014. Demographic, clinical and pathologic data were obtained and tabulated. Statistical analysis were performed to identify factors associated with pre-malignant and malignant lesion

RESULTS: A total of 180 patients were included in this study. Majority of the study population are below 50 years of age and are pre-menopausal. Eight cases were-malignant (n=2) and malignant (n=6). Diabetes mellitus, tamoxifen use and prolapsed endometrial polyps were the variables associated with pre-malignant and malignant lesions. Diabetes mellitus was the only strong predictor for malignancy (OR = 6.83).

CONCLUSION: Endometrial polyps are benign endometrial overgrowths common among premenopausal women. Known risk factors for malignancy in cases of endometrial polyps include age, menopausal status, abnormal uterine bleeding, hypertension, diabetes mellitus, obesity and large size of endometrial polp. In this study, only the presence of diabetes mellitus was interpreted as a significant predictor for either a pre-malignancy or malignancy.