An incidental nasopharyngeal carcinoma coexistent with primary nasopharyngeal tuberculosis
- Author:
Hon Syn Chong
1
;
Mohd Razif Mohammed Yunus
1
;
Norafidaah Ali
2
Author Information
- Publication Type:Case Reports
- MeSH: Human; Male; Adult; Nasopharyngeal carcinoma; Nasopharyngeal Neoplasms
- From: Philippine Journal of Otolaryngology Head and Neck Surgery 2014;29(1):23-25
- CountryPhilippines
- Language:English
- Abstract: p style=text-align: justify;strongOBJECTIVE: /strongTo describe a case of nasopharyngeal carcinoma coexistent with primary nasopharyngeal tuberculosis and review the literature.METHODS:br /Design:/strong Case Reportbr /strongSetting:/strong Tertiary Public University Hospitalbr /strongPatient:/strong One RESULTS:/strong A 28-year-old man presented with recurrent sore throat and neck pain with clinically enlarged tonsils. He underwent a routine adenotonsilectomy. Histopathologic examination revealed non-keratinizing squamous cell carcinoma with caseating granulomatous inflammation typical for tuberculosis in the same adenoid specimen. Nasopharyngeal carcinoma was staged T2bN2M0. He was treated with concurrent chemoradiotherapy and 9-month course of anti tuberculosis treatment. He recovered and remained symptom free year after treatment.CONCLUSION: /strongNasopharyngeal carcinoma (NPC) and tuberculosis (TB) are both very common diseases in Sabah, East Malaysia. However, it is very rare that both diseases present at the same time and same anatomical area in a patient. Diagnosis can be very challenging and confusing. Multidisciplinary consultations are warranted for appropriate treatment. Combined anti-tuberculosis treatment and concurrent chemoradiotherapy may be appropriate and effective./p
- Full text:55 pjohns.pdf
