Epidemiological pattern of retinoblastoma at the Philippine General Hospital
- Author:
Espiritu Romeo B.
;
de Jesus Arnel A.
;
Valera Eric G.
;
Mercado Gary V.
- Publication Type:Journal Article
- MeSH:
Human;
Male;
Female;
Infant;
RETINOBLASTOMA
- From:
Philippine Journal of Ophthalmology
2004;29(3):136-139
- CountryPhilippines
- Language:English
-
Abstract:
Methods: This is a retrospective case series of new retinoblastoma patients seen at the University of the Philippines-Philippine General Hospital (UP-PGH) in three periods: 1967 to 1977, 1985 to 1995, and 1997 to 2001. The demographic and clinical characteristics of retinoblastoma over the three periods were compared.
Results: The incidence of retinoblastoma increased from 40/100,000 new cases in 1967 to 1977 to 237/100,000 new cases in 1997 to 2001. The average age at onset did not change over time but the age at consultation decreased from 1.5 years to 1 year. The most common initial ocular manifestation at onset was cats eye reflex (77 to 79 percent) with findings of leukocoria (67 to 77 percent). Extraocular findings of proptosis and orbital mass declined through the years. Bilateral retinoblastoma comprised 30 percent in this series and showed no change in distribution over the years.
Conclusion: The epidemiological and clinical patterns of retinoblastoma cases at the Philippine General Hospital may be changing over time and requires continuous monitoring of incidence and characteristics.
