Beyond the X's and Y's: A case of complete androgen insensitivity syndrome
- Author:
Lipana Ma. Katherine R.
;
Tanangonan Gladys G.
- Publication Type:Journal Article
- MeSH:
ANDROGEN INSENSITIVITY SYNDROME
- From:
Philippine Journal of Reproductive Endocrinology and Infertility
2009;6():1-9
- CountryPhilippines
- Language:English
-
Abstract:
The Sex or sexuality is very complex subject. From a biological standpoint, the appearance of the external genitalia is only one parameter. Complete androgen insensitivity syndrome (CAIS), the most common form of male pseudohermaphroditism, embodies the multifaceted nature of this concept. Patients usually present with 46, XY karyotype with bilateral testes, female external genitalia, a shortened vagina, absent or rudimentary mullerian derivatives, normal breast development, and absent or scant pubic and axillary hair, as was the case in the patient presented herein. Prevalence ranges from 1 :20,400 to 1 :62,400 births. Its management often requires a multidisciplinary approach. Aside from addressing health risks, the psychosexual, social and ethical aspects of this condition should also be dealt with.
