Double-blind randomized clinical trial on the use of intravenous nalbuphine in post-cesarean patients on intrathecal morphine
- Author:
Obieta-Lopez Elaine F.
;
Lopez Carmelo
;
Celestino Lawrence
;
Dela Paz Cornelio A.
- Publication Type:Journal Article
- MeSH:
Human;
Female;
Adult;
INTRAVENOUS;
INTRATHECAL MORPHINE;
NALBUPHINE;
MORPHINE;
CESAREAN SECTION;
ANESTHESIA, SPINAL
- From:
Philippine Journal of Anesthesiology
2003;15(1):8-15
- CountryPhilippines
- Language:English
-
Abstract:
Sixty subjects who were to undergo elective cesarean section were randomized into two groups which received spinal anesthesia with 0.2 mg morphine for abdominal delivery. The Nalbuphine group received 10 mg IV Nalbuphine (Nubain) every 6 hours postoperatively while the patients in the control group were given saline. Pain, nausea and vomiting, pruritus and the incidence of respiratory depression were assessed in both groups for the first 24 hours and then compared and analyzed. Both the subjects and the investigators were blinded
The severity of nausea was significantly lower in the Nalbuphine group than in the Control groups while pruritus and pain scores failed to show any significant differences. None of the patients had any episodes of respiratory depression. (Author)
