Dexmedetomidine as part of a balanced anesthesia and the use of the proseal LMA in a patient with osteogenesis imperfecta for abdominal hysterectomy: a case report
- Author:
Layusa Clarissa Angela A.
;
Flores Olivia C.
;
Nagtalon Eric V.
;
Tjhin Suparto
- Publication Type:Case Reports
- MeSH:
Human;
Female;
Adult;
OSTEOGENESIS IMPERFECTA;
DEXMEDETOMIDINE;
ANESTHESIA;
AIRWAY MANAGEMENT
- From:
Philippine Journal of Anesthesiology
2009;21(2):79-86
- CountryPhilippines
- Language:English
-
Abstract:
Osteogenesis imperfecta is an inherited disorder of collagen with skeletal and extraskeletal manifestations that affect airway and anesthetic management of patients with the disease. This paper aimed to report a case of a patient with osteogenesis imperfecta for abdominal hysterectomy, discuss the anesthetic considerations of patients with the disease, describe balanced anesthesia using high dose dexmedetomidine as a primary agent and, use of ProSeal LMA for airway management.
A 44- year old female with osteogenesis imperfecta is scheduled for abdominal hysterectomy for molar pregnancy. Airway management was achieved with a ProSeal LMA, and surgery was conducted using balanced anesthesia with high dose dexmedetomidine, midazolam, fentanyl, atracurium and O2- nitrous oxide. Dexmedetomidine was given at concentrations ranging from 0.7 mcg/kg/hr to 3mcg/kg/hr without untoward adverse effects. No complications were observed intraoperatively and in the immediate postoperative period.
Dexmedetomidine is demonstrated to be safe and effective when used as part of a balanced anesthesia for patients with osteogenesis imperfecta. Likewise, the airway can be reliably managed with the use of a ProSeal LMA.