Andrenocortical carcinoma in pregnancy
- Author:
Ricero Claudette
- Publication Type:Journal Article
- MeSH:
Human;
Female;
Adult;
ADRENAL GLAND NEOPLASMS;
PREGNANCY
- From:
Philippine Journal of Reproductive Endocrinology and Infertility
2004;1(2):75-83
- CountryPhilippines
- Language:English
-
Abstract:
The first local case of a 37 year old Gravida 5 Para 3 (2-1-2-3) with adrenocortical carcinoma who developed metastases during pregnancy is reported. Patient initially presented with signs and symptoms of Cushings and virilization. Ultrasound revealed a solid suprarenal mass. Biochemical evaluation showed increased levels of urinary cortisol, 17-ketosteroids, serum testosterone and serum DHEA-S. Adrenalectomy revealed adrenocortical carcinoma. Complications developed at 31 weeks AOG necessitating early termination of pregnancy. In the absence of a more effective treatment modality, chemotherapy was started obtaining optimum outcome for both the mother and the fetus.
