Central Corneal Thickness and Corneal Endothelial Cells in Pseudoexfoliation Syndrome.
10.3341/jkos.2013.54.7.1060
- Author:
In Boem CHANG
1
;
Dong Won PAIK
;
Tai Jin KIM
;
Hyo Shin HA
;
Jung Hyun PARK
Author Information
1. Department of Ophthalmology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. hyuny@medimail.co.kr
- Publication Type:Original Article
- Keywords:
Central corneal thickness;
Corneal curvature;
Corneal endothelial cell density;
Pseudoexfoliation syndrome
- MeSH:
Cataract;
Endothelial Cells;
Exfoliation Syndrome;
Glaucoma;
Humans;
Intraocular Pressure;
Medical Records;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
2013;54(7):1060-1065
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the central corneal thickness (CCT) and corneal endothelial cell density (ENDO) in pseudoexfoliation syndrome. METHODS: Medical records of patients who underwent a preoperative examination for cataract surgery and an examination for glaucoma were retrospectively reviewed. The present study included 44 patients (59 eyes) and age- and sex-matched controls. The total pseudoexfoliation patients divided into 2 groups, such as pseudoexfoliation syndrome (28 eyes) and pseudoexfoliative glaucoma (21 eyes) .The intraocular pressure (IOP), CCT, ENDO, corneal curvature (CC) and axial length (AL) were measured. RESULTS: The total pseudoexfoliation group showed significantly higher IOP (p = 0.001), thinner CCT (p = 0.003) and lower ENDO (p = 0.037). The pseudoexfoliation syndrome group showed significantly thinner CCT (p = 0.010) and lower EDNO (p = 0.041), but no significant difference in IOP (p = 0.941). There was no significant difference in CCT (p = 0.060) and ENDO (p = 0.171) between the pseudoexfoliative glaucoma group and controls, but the pseudoexfolliative glaucoma group showed significantly higher IOP (p < 0.001). CONCLUSIONS: The pseudoexfoliation group showed thinner CCT which should be taken into consideration when evaluating IOP with the applanation tonometer and diagnosing glaucoma, especially in pseudoexfoliation syndrome patients.
