Prevalence and Risk Factors of Peripheral Artery Disease in Elderly Chronic Ischemic Stroke Patients: A Study of a Single Geriatric Hospital.
- Author:
Bum Joon KIM
1
;
Jae Hoon KANG
;
Deok Hyeon SOHN
Author Information
- Publication Type:Original Article
- Keywords: Cerebral infarction; Peripheral artery disease; Ankle brachial index
- MeSH: Aged; Ankle Brachial Index; Atherosclerosis; Blood Urea Nitrogen; Cerebral Infarction; Cholesterol; Coronary Artery Disease; Hematologic Tests; Humans; Hypercholesterolemia; Logistic Models; Peripheral Arterial Disease; Prevalence; Risk Factors; Stroke
- From:Journal of the Korean Geriatrics Society 2012;16(1):5-11
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND: Peripheral artery disease (PAD), which is caused by atherosclerosis of the peripheral vessels, is a progressive disease, especially in patients with many of the vascular risk factors. The aim of this study was to investigate the prevalence and risk factors of PAD in elderly chronic stage ischemic stroke patients in Korea. METHODS: Ninety-six elderly patients (> or =60 years) admitted to a local geriatric hospital with ischemic stroke in the chronic stage (mean duration of stroke, 590 days) were included in this study. Vascular risk profiles, routine blood tests, severity of stroke and ankle-brachial index (ABI) were measured. RESULTS: Of the 96 patients, 55 (57.3%) had PAD (ABI<0.9) of which 6 patients (6.3%) had severe PAD (ABI<0.5) and 22 patients (22.9%) had bilateral PAD. PAD was more frequently observed in patients with diabetes (65% vs. 15%, p=0.001), hypercholesterolemia (65% vs. 15%, p<0.001), previous history of coronary artery disease (CAD) (25% vs. 5%, p=0.01) and recurrent ischemic stroke (36% vs. 12%, p=0.01). The means of the total cholesterol and blood urea nitrogen were higher in patients with PAD. From the results of the binary logistic regression analysis, presence of diabetes (odds ratio [OR], 4.740; p=0.026), hypercholesterolemia (OR, 18.991; p<0.001), previous history of CAD (OR, 7.579; p=0.038) and lower Korean version of Modified Barthel Index (OR, 0.971; p=0.009) were independent risk factors for PAD. CONCLUSION: PAD is frequently observed in elderly patients with chronic ischemic stroke. Measuring ABI to diagnose PAD and controlling risk factors may be beneficial in these patients seen at geriatric hospitals and centers.
