Investigation on elimination of two optic isomers of chlorpheniramine in urine on experiments in man
- Author:
Bui Tung Hiep
- Publication Type:Journal Article
- Keywords:
chlorpheniramine, urine
- MeSH:
Chlorpheniramine;
Urine;
Methods
- From:Pharmaceutical Journal
2004;44(2):42-43
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The elimination of chlorpheniramine (CPAM) racemic isomers from human urine in experiment. The pharmacokinetic elimination of chlorpheniramine in the product contac including racemic chlorphenyramine and phenylpropano …was assessed in 9 health men and 9 women administrating 8mg racemic chlorphenyramine in Contac after an overnight fast. Urine samples were collected up to 144 hours and individual enatiomers of chlorpheniramine was defermined by HPLC method. There was no difference in the elimination of unchanged CPAM in urine from male and female subjects
