Study on the Mechanism of Health Protection of Mongolian Medicine Polyginatum Odoratum
- VernacularTitle:Солилцооны бүлгийн ухаанд суурилсан монгол эм мухар цагааны хүчжүүлж шимжүүлэх үйлдлийн судалгаа
- Author:
Chang Chun, M.Munkhtsetseg, E.Enkhsuren, Cheng Hong Mei, Wang Xiu Lan
- Collective Name:Inner Mongolian University for Nationalities
- Publication Type:Journal article
- Keywords:
Mongolian drug;
Polygonatum odoratum;
Biomarkers;
UPLC-MS
- From:
Mongolian Pharmacy and Pharmacology
2017;10(1):22-26
- CountryMongolia
- Language:Mongolian
-
Abstract:
Objective: To explore the effects of Polygonatum odoratum on body based on metabonomics.
Methods: The ultra performance liquid chromatography coupled with mass spectrometry (UPLC-MS) and principle component analysis(PCA) and orthogonal partial least squares discriminant analysis(OPLS-DA) were used to evaluate the changes of endogenous substances in rats after intragastric administration of Polygonatum odoratum.
Results: Significant differences between the control group and administration group were observed in PCA and OPLS-DA model. Five potential biomarkers between control group and administration group were identified. The relative content of Alpha-Tocotrienol, PC(14:1(9Z)/14:1(9Z)), Stearic acid, Theasapogenol A, Docosahexaenoic acid increased.
Conclusion: The biomarkers had many beneficial activities, so the Mongolian medicine Polygonatum odoratum had the function of health care.
Key words: Mongolian drug; Polygonatum odoratum; Biomarkers; UPLC-MS
- Full text:W020170427501815719115.pdf
