Study of the Biological Activities Preparation with Tribulus Terrestris l. on Free Serum Testosterone Changes in Male Rats
- VernacularTitle:Зэлэн зангуу (tribulus terrestris l.) агуулсан бэлдмэлийн үйлдлийг хархны ийлдсэн дэх тестостероны агууламжаар тодорхойлсон судалгааны үр дүн
- Author:
Т.Даваасамбуу, С.Бадамцэцэг, Б.Оюунчимэг, А.Баянмөнх, Б.Бадамцэцэг, Л.Лхавга, Л.Хүрэлбаатар
- Collective Name:Drug Research Institute
- Publication Type:Journal article
- Keywords:
Tribulus Terrestris L, Free testosterone, Dihydrotestosterone, Protodioscin
- From:
Mongolian Pharmacy and Pharmacology
2017;10(1):17-21
- CountryMongolia
- Language:Mongolian
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Abstract:
Wistar nonlinear rats weighing 170-220g. Rats were divided 5 groups, including control group, group-1, group-2, group -3 and reference group. Dried thistle extract and raw bovine testicle were contained by 1:1, 1:2 and 2:1 ratio. Each 0.1g ratio was dissolved in 20 ml distilled water and administered 2 times per day. Blood sampling was done for each rat after 3, 7, 14, 21, 28 and 35 days. Their testosterone level was measured by ELISA Kit.
Results: The results indicated that free serum testosterone level in male rats increase and decrease in 7 days frequency. All tested groups showed gradual increase in the level of free serum testosterone when compared to that of corresponding control (p<0.05). Statistical comparison of all groups revealed that the maximum level was found in group 1. Moreover, group 3 was showed gradually increase in level of free serum testosterone, irrelative with period of decrease testosterone level.
Conclusion: According to our results and previous study, it is suggested that preparation with Tribulus terrestris L. extract could be used in the androgen deficiency and erectile dysfunctions.
Keywords: Tribulus Terrestris L, Free testosterone, Dihydrotestosterone, Protodioscin
- Full text:W020170427501054312433.pdf
