Some Results of the Study on the Technology of Suppository with Garlic Extract
- VernacularTitle:Сармисны ханд бүхий лаа эмийн хэлбэрийн технологийн судалгааны зарим үр дүнгээс
- Author:
Purevjargal.B
;
Otgondari.B
;
Khongorzul.D
- Publication Type:Journal article
- Keywords:
garlic extract;
suppository
- From:
Mongolian Pharmacy and Pharmacology
2016;9(2):8-10
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background: In the world there are 400 million people affected by pinworm disease and children
aged 5-12 comprise of 10-90% in the epidemic center.
Purpose: Main goal is to process the technology of the suppository with garlic extract.
Materials and methods:130.0 gram Uliastai sort garlic with red husk (Allium sativium, Liliaceae)
and 70 percent ethyl spirit 1:1. The experiment determined suppository bioavailability prepared
from 3 types of base rated with cacao paraffin (80:20), cacao: paraffin (70:30), cacao from garlic
extract on the turning basket equipment in the condition (pH=8) and measured it UV mini-1240
spectrometer in 240 nm.
Results: From the results, we noticed that as for suppository bioavailability cacao base with 5
percent garlic extract prepared from 3 different bases, was 1.37 times more than cacao: paraffin
base (70:30) and 5.23 times more than (80:20). We processed the technology scheme of suppository
with 5 percent garlic extract. Suppository bioavailability cacao: paraffin (70:30), prepared from
cacao base was better than cacao: paraffin base (80:20).
Key words: garlic extract, suppository, bioavailability
- Full text:W020170427506506187248.pdf
