Coronary flow grade is independent predictor of improved left ventricularfunction in patients with acute myocardial infarction treated by primary PCI: a two-dimensional speckle tracking study
- VernacularTitle:Зүрхний цочмог шигдээсийн үед титэм судсан дотуурх эмчилгээний дараах титмийн цусны урсгал, зүүн ховдлын ерөнхий стрейн үзүүлэлт хоорондын хамаарал
- Author:
Batmyagmar Kh
;
Surenjav Ch
;
Amarjargal B
;
Lkhagvasuren Z
- Publication Type:Journal Article
- Keywords:
AMI;
LV function;
primary PCI;
global longitudinal strain;
TIMI flow grade
- From:Mongolian Medical Sciences
2016;178(4):23-28
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction
Coronary TIMI flow gradewas previously demonstrated to be related to outcome after acute myocardial
infarction. However, the relationship between coronary flow grade and left ventricular global longitudinal
strainin patients with acute myocardial infarction (AMI) treated by primary percutaneous intervention
(PCI) were unclear.
Goal
In this study, we aimed to reveal the relationship between coronary TIMI flow grade and LV GLS in
patients with AMI.
Materials and Methods
We prospectively selected patients with AMI who treated by primary PCI. Based on whether TIMI 3
flow achieved at the end of the procedure patients were divided into two groups. Group I (TIMI 3 flow
was achieved, n=367), Group II (TIMI 3 flow was not achieved, n=47). The LV GLS was assessed by
2dimensional speckle-tracking echocardiography (2D STE).
Results
A total of 413 patients (mean age 60±13, 84% male) were included and TIMI 3 flow was achieved in
367 patients (88%). LV GLS was significantly impaired in patients who had TIMI 3 flow not achieved
compared with TIMI 3 flow achieved group (-13.1±4.8% vs. -15.3±3.8%, p<0.001). Multiple linear
regression analysis which included age, gender, clinical, biochemical and angiographic variables
showed that coronary TIMI flow grade of culprit artery was independently associated with LV GLS. There
was negative correlation between coronary TIMI flow grade and LV GLS (Pearson’s r=-0.183, p<0.001).
Simple linear regression analysis revealed that coronary TIMI flow grade is directly associated with LV
GLS (β=-1.61, p<0.001) and which indicated that every 1 scale increase of final coronary TIMI flow
grade resulted -1.61% increase of LV GLS.
Conclusion
Our study demonstrated the coronary TIMI flow grade of the culprit artery was independently associated
with LV GLSin patients with AMI treated by primary PCI.
- Full text:P020170420820631034655.pdf
