The identifi cation results for the diagnostic sensitivity of cervical liquid based cytology testing
- VernacularTitle:Умайн хүзүүний шингэнд суурилсан эс судлалын шинжилгээний оношлогооны мэдрэг чанарыг тодорхойлсон дүн
- Author:
Batchimeg Ts
;
Gerelee Kh
;
Sayamaa L
;
Munkhtulga L
;
Bayarmaa E
- Publication Type:Journal Article
- Keywords:
cytology;
cervical cancer;
liquid-based cytology;
Pap smear;
screening
- From:Mongolian Medical Sciences
2016;175(1):26-30
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction
Cervical cancer screening program is using conventional Pap smear (CPS) have been successfully
used in Mongolia, but new kind of test as “Liquid based cytology” (LBC) is not popular for screening.
This liquid based cytology testing might reduce the number of unsatisfactory smears, and increase the
accuracy of diagnosing.
Goal
The main aim of this study was to assess diagnostic accuracy and sensitivity of Liquid based cytology
versus Conventional Pap smear using ‘split-samples’ technique.
Materials and Methods
This was cross sectional study, total of 75 cervical split samples were included over a period of 2 months.
Split sample was obtained using cervix-brush. CPS was prepared from brush and the brush head was
suspended in the Liquid based vial and processed by LBC method and pap staining. Smears were
diagnosed by cytologists. Abnormal smears were concluded by cervical biopsy as a Golden Standard.
Results
There were 14%unsatisfactory smears in CPS and 6% in LBC; the main cause is insuffi cient cells, and
excess blood in CPS. LBC had diagnostic accuracy of LSIL was lower, but ASC-US was higher than
CPS was signifi cant. LBC (100%) was more sensitive than CPS (89%) was confi rmed by biopsy.
Conclusions: LBC testing was successfully reduced unsatisfactory smears rate. LBC samples offered
better clarity and uniform spread of smears, less time for screening and better diagnostic accuracy of
LSIL and ASC-US than CPS.
- Full text:P020170419825844009336.pdf
