Advancing clinical, laboratorial and computer tomographical diagnosis of acute pancreatitis
- VernacularTitle:Цочмог панкреатитын эмнэлзүйн, лаборатори ба компьютерт томографи оношлогооны зарим асуудлыг боловсронгуй болгох нь
- Author:
Badamsed Ts
- Publication Type:Journal Article
- Keywords:
borders;
density;
size;
structure;
shape
- From:Mongolian Medical Sciences
2010;152(2):16-23
- CountryMongolia
- Language:Mongolian
-
Abstract:
INTRODUCTION: There have been limited research studies done in Mongolia on clinical, laboratorial and computer
tomographical diagnosis of acute pancreatitis.
GOAL: Our study aims to examine clinical, laboratorial and CT symptoms diagnosis of acute pancreatitis, to diagnose
the different types of acute pancreatitis, and to develop diagnostic criteria based on CT for differentiating among those
types.
OBJECTIVES:
1. To study clinical symptoms of acute pancreatitis
2. To determine alpha amylase, ALAT, ASAT, and the amount of glucose.
3. To determine CT symptoms for the types of acute pancreatitis.
4. To develop diagnostic criteria based on CT for differentiating among those types
MATERIALS AND METHODS: Over the years of 2006 to 2010, we have studied the CT symptoms of 59 patients diagnosed
as having acute pancreatitis, and the clinical and laboratorial symptoms of 81 patients with the same disease, with the
help of health facilities at Diagnostic Imaging Department of the “Achtan-elite” general hospital and “Friendship-Naran”
diagnostics center.
The scanners such as CT-W-4 type scanner of Japanese Toshiba Corporation, MSCT Presto (made in 2007 by Hitachi,
Japan) and CT Max 640 type scanner of USA General Electric Corporation have been used for the diagnostics.
We successfully calculated the amount of alpha amylase, ALAT, and ASAT with colorimetric analysis. For this calculation,
we used amylase detector manufactured by German Human Firm. Sugar amount was measure by fermentive oxidization
with dioxide-glucose.
The acute pancreatitis inflammation, hemorrhage, necrosis and its various forms, and diagnosis have been
proved by the brief x-ray imaging of the abdomen, x-ray with contrast injections for stomach and upper intestine,
Ultrasonic, Celliacography, MRI, Cytology, Biopsy analysis and surgery.
All the results were presented in commonly used statistical ways, taking into account possible calculation errors,
and probabilities were checked with Student’s t-distribution.
CONCLUSION:
1. During acute pancreatitis, 56.8%±5.5 suffered from abdominal shooting pain, 28.3%±5.0 from stomach cramps,
79.0%±4.5 from diarrhea, 91.4%±3.1 from fever, and 56.8%±5.5 from abdominal hemorrhage.
2. The amount of alpha amylase in blood serum increased 6 times the amount of ASAT/ALAT 3 to 5 times.
3. By CT scanning, we have found more common CT symptoms such as sharp border edges of pancreas in swollen
acute pancreatitis (in 69.2%±9.2 of the patients), entire and partial enlargement of the pancreas (in 73.1%±8.9
of the patients), fluid collection in the stomach rear room (in 61.1%±11.8 of the patients), in hemorrhage acute
pancreatitis and uneven density reduction (in 66.7%±12.6 of the patients) and fluid collection in the stomach
rear room (in 86.7%±9.1 of the patients), in necrosis type of acute pancreatitis respectively.
4. Shape, size, structure, density, borders, interaction with surrounding body organs, change in pancreas density
after contrast injection and accumulated fluid in the rear stomach are identified as the main criteria to diagnose
acute pancreatitis types and differentiate among them.
5. CT diagnostics of the acute pancreatitis types and differentiating among them are very crucial to select
appropriate acute pancreatitis treatment on time.
- Full text:P020151216359010507358.pdf
