Vaginal Brenner tumor with literature review: does this tumour originate from Walthard nests?
- Author:
Sanghui Park
;
Min-Sun Cho
- Publication Type:Case Reports
- Keywords:
Brenner tumour, vagina, Walthard nest
- From:The Malaysian Journal of Pathology
2017;39(1):89-93
- CountryMalaysia
- Language:English
-
Abstract:
Vaginal Brenner tumor is extremely rare. Only five cases have been reported in the English literature
to date. Here we report a vaginal Brenner tumor in a 76-year old postmenopausal woman, who
presented with a 2.5cm-sized sessile vaginal polyp. Microscopically, it showed characteristic features
of Brenner tumor consisting of three components; transitional islands, glands, and dense fibrous
stroma. The epithelial tumor cells were positive for GATA-3, p63 and ER, but negative for PAX8.
The origin of Brenner tumors in the vagina is unclear, but previous reports suggested of Müllerian
origin. However, our case revealed that vaginal Walthard nests could be possible precursor lesions
based on their immunohistochemical staining results.
- Full text:P020170515590735400138.pdf
