Primary Cutaneous T Cell Lymphoma (Gamma Delta subtype)
- Author:
Yong Khee Guan
;
Chye Chung Gan
- Publication Type:Case Reports
- Keywords:
Cutaneous lymphoma;
Gamma delta subtype;
T cell lymphoma
- From:
The Medical Journal of Malaysia
2016;71(5):296-297
- CountryMalaysia
- Language:English
-
Abstract:
Primary cutaneous T-cell lymphoma gamma-delta subtype is
an extremely rare entity of all the cutaneous T-cell
lymphomas. Our case provides an insight on clinical
behavior and treatment response with feasible effective
combination chemotherapy. We believe this will be of great
interest to clinicians when facing this difficult clinical entity.
We present a case of a 66-year-old Malay man with a threeweek
history of rapidly growing skin nodules and plaques
which spread throughout his body. He was commenced on
combination chemotherapy gemcitabine, etoposide, and
carboplatin with near complete remission on completion of
second cycle but he defaulted. He relapsed within a month
and he progressed despite treatment with the same regime.
He was salvaged with fludarabine, cytarabine, and
vinblastine combination chemotherapy but progressed with
brain metastasis and died. However, more investigations
and studies need to be done in this relatively unknown rare
entity. A rare lymphoma registry might be of help to better
understand and treat similar conditions.
- Full text:W020170208382923041432.pdf
