Rare post-operative complications in a previously undiagnosed Congenital Factor X deficiency patient
- Author:
Mohd Nazri H
;
Suhair AA
;
Wan Suriana WAR
;
Zefarina Z
;
Azlan H
;
Wan Zaidah A
- Publication Type:Case Reports
- Keywords:
Congenital bleeding disorder;
Factor X;
factor deficiency;
post-operative bleeding
- From:The Malaysian Journal of Pathology
2016;38(3):327-331
- CountryMalaysia
- Language:English
-
Abstract:
Factor X (FX) deficiency is a rare autosomal recessive congenital bleeding disorder. The clinical
presentation is among the most severe among the rare coagulation defects. Thus, majority of
diagnosed patients will receive factor replacement therapy before surgical manipulation. However,
the diagnosis of FX deficiency may be overlooked because it is a rare entity. This is a case report
of a 15-year-old male patient who was diagnosed with FX deficiency after developing post-operative
complications. With regular fresh frozen plasma infusion given, the patient responded well and
recovered. However, had he been diagnosed earlier pre-operatively, the post-operative complication
could have been prevented. Therefore, pre-operative coagulation screening should be performed
in patients with significant bleeding history in both emergency and elective situations to prevent
surgical morbidity related to post-operative bleeding.
