Rituximab-induced lung disease
- Author:
Wan Asyraf Wan Zaidi
;
Wan Fariza Wan Jamaludin
;
Nor Rafeah Tumian
;
Fadilah Abdul Wahid
- Publication Type:Case Reports
- Keywords:
Rituximab-induced lung disease;
acute respiratory distress syndrome
- MeSH:
Rituximab;
Lung Diseases
- From:
The Medical Journal of Malaysia
2016;71(4):209-210
- CountryMalaysia
- Language:English
-
Abstract:
Pulmonary toxicity is a rare complication of Rituximab
therapy. Although Rituximab is relatively safe and can be
administered in an outpatient setting, Rituximab-associated
lung disease has been reported and may cause mortality
despite early detection. Typically the pulmonary toxicity
occurs at around the fourth cycle of Rituximab. High index
of suspicion is crucial and other concurrent pathology such
as infective causes should be excluded. Radiological
imaging and histological confirmation should be obtained
and early treatment with corticosteroid should be initiated.
Patients should receive counselling regarding respiratory
symptoms and possible pulmonary toxicity.
- Full text:P020161107419453307614.pdf
