Myopericytoma - A Unifying Term Or A Unique Entity?
- Author:
Zeeba S Jairajpuri
;
Md Jaseem Hasan
;
Garima Baweja Madan
;
Sujata Jetley
- Publication Type:Case Reports
- Keywords:
soft tissue tumour;
perivascular myoid cell;
concentric perivascular pattern;
myopericytoma;
hemangiopericytoma
- From:The Malaysian Journal of Pathology
2016;38(2):159-163
- CountryMalaysia
- Language:English
-
Abstract:
Myopericytoma are uncommon, slow-growing benign perivascular neoplasms that show
hemangiopericytoma-like vascular pattern. We report a 52-year-male patient with a painless palpable
nodule in the left thumb for the past 9 months. The mass, on the thenar aspect, was 15x12mm in
size. X-ray revealed a soft tissue swelling with no bony association. The excised nodule was a
non-capsulated, well-circumscribed vascular neoplasm composed of proliferating spindle to ovoid
bland cells with eosinophilic cytoplasm. A concentric perivascular arrangement of the cells was
seen interspersed by thin-walled, branching, staghorn blood vessels. Nuclear atypia, mitotic figures
and necrosis were not observed. Immunohistochemistry revealed diffuse positivity of the tumour
cells for smooth muscle actin while staining negative for CD34 and desmin - features suggestive
of origin from the perivascular myoid cell. Morphological features of myopericytoma are shared
with hemangiopericytoma, glomus tumors, myofibroma and solitary fibrous tumour which form the
important differential diagnoses. It is a relatively newly described disease entity recognized by the
World Health Organisation classification of tumours.
- Full text:P020161005047068643699.pdf
