Thyroid metastasis of bladder transitional cell carcinoma
- Author:
Seyyed Mohammad Mehdi Mirjalili
;
Sima Hashemipour
;
Sohrab Selehi
;
Amir Mohammad Kazemifar
;
Parisa Sadat Madani
- Publication Type:Case Reports
- Keywords:
transitional cell carcinoma of bladder;
thyroid metastasis
- From:The Malaysian Journal of Pathology
2016;38(1):65-70
- CountryMalaysia
- Language:English
-
Abstract:
The thyroid gland is a rare site for cancer metastasis. We report a 75-year-old man who was
referred with a history of hematuria and generalized bone pain for the past few months. He had a
past history of partial left lobe thyroidectomy for follicular adenoma. Subsequently he was referred
for a thyroid mass and a subtotal thyroidectomy showed a poorly-differentiated carcinoma. On the
latest admission, the patient underwent resection of a bladder tumour with malignant histology and
an immunohistochemical profile of CK7+/CK20+/34 Beta E12+/CEA-/PSA-. Re-examination of
thyroid sections with immunohistochemical stains revealed the malignant cells to be CK7+/CK20+/34
Beta E12+/CEA-/TTF1-. The findings were compatible with metastasis of the bladder transitional
cell carcinoma to the thyroid gland.Scans revealed multiple liver and bone metastases. The patient
died 2 months after the diagnosis.
- Full text:P020160601520243652464.pdf
