Haematological and biochemical markers as predictors of dengue infection
- Author:
Rashmi Mv
- Publication Type:Journal Article
- Keywords:
dengue fever, hematological parameters, biochemical parameters
- From:The Malaysian Journal of Pathology
2015;37(3):247-251
- CountryMalaysia
- Language:English
-
Abstract:
Dengue is a viral infection which has become a serious problem in recent years. It is a major cause
of mortality and morbidity. The present study is a prospective, hospital-based, observational study
done from August 2014 to October 2014. The objective of our study was to consider whether dengue
infection can be suspected based on haematological and biochemical findings. The study included
100 patients positive for dengue infection. Complete hemogram, transaminases for liver injury,
blood urea and serum creatinine levels for renal assessment were performed for these patients. The
most common haematological findings were thrombocytopenia, leucopenia, an increase in the mixed
cell fraction of the leucocytes and the presence of reactive lymphocytes. Biochemical parameters
like the aminotranferases, blood urea and serum creatinine levels were significantly raised. Hence,
a platelet count of <100,000 cells/μl, leucopenia of <4000cells/μl and aspartate aminotransferase
levels of >82.2 U/L can be considered as predictors of dengue infection.
- Full text:P020160315415544101433.pdf