The relation between immunocompromised status and Strongyloides stercoralis infection: case-control study
- Author:
Dewi Masyithah Darlan
- Publication Type:Journal Article
- From:Tropical Biomedicine
2015;32(4):644-649
- CountryMalaysia
- Language:English
-
Abstract:
Strongyloides stercoralis infection is caused by intestinal nematodes in the human
body, which in immunocompromised individual, may cause severe morbidity and fatality. This
study aimed to reveal the current prevalence of S. stercoralis infection among the stool
samples sent to Parasitology Laboratory FMUI and identify its association with the status of
immunocompromised. A case-control study with consecutive sampling method was, conducted
between March-June 2013. Subjects were the patients of hospitals/laboratory who sent their
stool samples to the Parasitology laboratory of FMUI. All stools were examined through
direct examination, followed by Harada-mori culture. The immune status of the patients was
identified through their medical records. The total number of stools collected was 170 consisted
of 108 males and 62 females. The age of the patients ranged from 2 to 80 years old (average
33.41±22.65 years); 18.2% (31/170) was immunocompromised and 81.8% (139/170) was
immunocompetent. A total of 18/170 (10.6%) stools were positive of S. stercoralis larvae; 6
stools (19.4%, 6/31) were from the immunocompromised and 12 stools (8.6%, 12/139) originated
from the immunocompetent. The result suggested that immunocompromised status has a
positive relation towards S. stercoralis infection. Results from this study could serve as input
for clinicians for better management of cases with diarrhoea, especially among the
immunocompromised.
- Full text:P020160316382722859892.pdf
