Surfactant replacement therapy for prevention and treatment of respiratory distress syndrome of preterm infants
- Author:
Nguyen Trong Hieu
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome
- MeSH:
Respiratory Distress Syndrome, Adult;
Respiratory Distress Syndrome;
Newborn;
Therapeutics;
Pulmonary Surfactants;
Prevention & control;
Therapeutics
- From:Ho Chi Minh city Medical Association
2005;10(3):132-134
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
During the period between 1999 and 2005, a clinical trial has been conducted at Hung Vuong Hospital to assess the efficacy of surfactant replacement therapy for prevention and treatment of respiratory distress syndrome (RDS) in preterm infants. Results: A total of 83 preterm infants with gestational age from 27 to 33 weeks were recruited, of whom 45 assigned to the prophylactic group and 38 to the rescue group. Percentages of developing or not reassuring RDS were 5.4% and 21.1% in the prophylactic and the rescue group, respectively (p<0.001). However, the difference in neonatal mortality was not statistically significant: 8.9% in the prophylactic in comparison with 15.8% in the rescue group
