Contrast enhanced Voiding Urosonography (ce-VUS) as a radiation-free technique in the diagnosis of vesicoureteric reflux: Our early experience
- Author:
Faizah Mohd Zaki
;
Hamzaini Abdul Hamid
;
Kanaheswari Yoganathan
;
Dayang Anita Abdul Aziz
;
Zulfiqar Muhamed Annuar
- Publication Type:Journal Article
- MeSH:
Urinary Tract Infections
- From:
The Medical Journal of Malaysia
2015;70(5):269-272
- CountryMalaysia
- Language:English
-
Abstract:
Objective: Contrast-enhanced ultrasound has become
increasingly utilised as an alternative imaging modality for
the diagnosis of vesicoureteric reflux (VUR) in paediatric
patients. The study objective is to evaluate the efficacy of
contrast enhanced Voiding Urosonography (ce-VUS)
compared with fluoroscopic micturating
cystourethrography (MCU) in the detection of VUR.
Methods: This prospective study was carried out between
July 2011 and January 2013 on paediatric patients who
underwent MCU. All consented patients would undergo ceVUS
prior to MCU. We documented the epidemiology details,
the number of Kidney-Ureter (K-U) unit studied, baseline
renal and bladder sonogram, as well as presence of VUR on
ce-VUR. The technique for ce-VUS was standardized using
normal saline to fill the bladder prior to administration of
SonoVue® (2.5 ml) to assess the kidney-ureter (K-U) unit.
Dedicated contrast detection software was used to discern
the presence of microbubbles in the pelvicaliceal system
(PCS). The findings were then compared with MCU.
Results: 27 paediatric patients were involved in the study [17
males (63%) and 10 females (37%)] involving 55 K-U units
(one patient had a complete duplex system). MCU detected
VUR in 10 K-U units while ce-VUS detected VUR in 8 out of
the 10 K-U units. There were 2 false negative cases (both
Grade 1) with ce-VUS. The sensitivity, specificity, accuracy,
positive predictive value, and negative predictive value of
ce-VUS were 80%, 98%, 95%, 89% and 96%, respectively.
Conclusion: ce-VUS is a sensitive and specific radiation-free
alternative for the detection of VUR in the paediatric
population.
- Full text:P020151109523957724769.pdf
