Neurogenous hyperplasia in the oesophagus
- Author:
Tuba Kara
;
Iclal Gurses
;
Ebru Serinsoz
;
Rabia Bozdogan Arpaci
;
Enver Ucbilek
;
Ayse Polat
- Publication Type:Case Reports
- Keywords:
Neurogenous hyperplasia;
oesophagitis;
Barrett’s oesophagus
- From:The Malaysian Journal of Pathology
2013;35(1):99-102
- CountryMalaysia
- Language:English
-
Abstract:
Leiomyoma and gastrointestinal stromal tumours take fi rst place among mesenchymal tumours of the
oesophagus, where tumours of peripheral nerve origin are rarely seen. Schwann and enterochromaffi n
cell proliferation occur in neurogenous hyperplasia, an entity observed in the appendix which has not
been reported in the oesophagus in the medical literature. Oesophagogastroscopy of a 58-year-old
woman showed linear erosions and nodularity at the gastroesophageal junction. The microscopic
examination of biopsies taken from this area revealed proliferation of spindle cells with oval-round
nuclei forming focal fascicular arrangement in the lamina propria. These cells stained positive for
synaptophysin and S100-protein, while immunohistochemistry for smooth muscle actin and CD117
were negative. The case was diagnosed as neurogenous hyperplasia with these fi ndings. Control
endoscopic biopsies showed no evidence of neurogenous hyperplasia. Neurogenous hyperplasia can
be considered as a distinct entity which might also be observed in the oesophagus as in the appendix.
- Full text:P020150925383153882114.pdf
