Comparison of Abtectcell III and Diamed red cell antibody screening kit for detection of clinically significant red cells alloantibody
- Author:
Sharifah Mai Sarah Syed Azim
;
Nor Asiah Muhamad
;
Leong Chooi Fun
;
Noor Hamidah Hussin
- Publication Type:Journal Article
- Keywords:
blood groups;
RBC antigens and antibodies;
vMNS
- From:The Malaysian Journal of Pathology
2015;37(2):109-114
- CountryMalaysia
- Language:English
-
Abstract:
Antibody screening is important for the antenatal screening and pre-transfusion tests. This study
aimed to compare the MUT/Mur kodecytesAbtectcell III (CSL Abtectcell III) red cell antibody
screening kit with DiaMed ID-Dia Cell I-II-III Asia that was then used in our laboratory. In this
study, 125 samples were randomly chosen, with 67 samples of known antibody specificities and
58 samples identified as negative for antibody, as the negative control. Concordant negative results
were obtained in 57 out of 58 antibody negative samples. Concordant antibody positive results
with both reagents were seen in 49 out of 67 samples. There were 18 discrepant results of antibody
screening with CSL Abtetcell III (16/18 for vMNS antibodies). The sensitivity and specificity for
CSL Abtectcell III were 73.0% and 98.3% respectively. In conclusion, the CSL Abtectcell III reagent
would be an acceptable alternative for screening of red cell alloantibodies. It was able to detect all
the clinically significant alloantibodies.
- Full text:P020150915520389617730.pdf
