Individualised second line anti-tuberculous therapy for anextensively resistant pulmonary tuberculosis (XDR PTB) in East Malaysia
- Author:
Muhammad Redzwan S Rashid Ali
;
Anna P Ralph
;
Kunji Kannan Sivaraman Kannan
;
Timothy William
- Publication Type:Case Reports
- MeSH:
Extensively Drug-Resistant Tuberculosis
- From:
The Medical Journal of Malaysia
2015;70(3):200-204
- CountryMalaysia
- Language:English
-
Abstract:
Clinical experience with extensively Drug Resistant
tuberculosis (XDR-TB) has not been reported in Malaysia
before. We describe the clinical characteristics, risk factors,
progress and therapeutic regimen for a healthcare worker
with XDR-TB, who had failed therapy for multidrug resistant
TB (MDR TB) in our institution. This case illustrates the risk
of TB among healthcare workers in high TB-burden settings,
the importance of obtaining upfront culture and
susceptibility results in all new TB cases, the problem of
acquired drug resistance developing during MDR-TB
treatment, the challenges associated with XDR-TB treatment
regimens, the value of surgical resection in refractory cases,
and the major quality of life impact this disease can have on
young, economically productive individuals.
- Full text:P020150904426559968290.pdf
