Hypercalcemic Crisis – A Fatal Case of Primary Hyperparathyroidism
- Author:
Yueh Chien Kuan
;
Florence Tan
- Publication Type:Case Reports
- Keywords:
Primary hyperparathyroidism;
hypercalcemic crisis;
pathologica fracture;
urolithiasisl
- From:
The Medical Journal of Malaysia
2014;69(6):277-278
- CountryMalaysia
- Language:English
-
Abstract:
We describe the clinical presentation, investigation and
management of an eventually fatal case of hypercalcemic
crisis due to primary hyperparathyridism (PHPT).
A 60 year-old lady with history of urolithiasis presented with
worsening generalized bone pain, spinal scoliosis and a
limp. Laboratory data showed hypercalcemia and raised
alkaline phosphatase. Left hip x-ray revealed a subcapital
femoral neck fracture. Intact parathyroid hormone was
elevated, 187.6 pmol/L (1.6 – 6.9) and ultrasound showed an
enlarged right parathyroid gland. Despite initial reduction of
serum calcium with saline infusion and multiple doses of
intravenous pamidronate, her calcium increased to 4.14
mmol/L a week following application of Buck’s traction for
persistent left hip pain. She succumbed eventually with
serum calcium peaking at 6.28 mmol/L despite multiple
therapeutic interventions.
- Full text:P020150729479273816241.pdf
