Suboptimal Therapy for Dyslipidaemia in Coronary Bypass Surgical Patients with Premature Ischaemic Heart Disease
- Author:
Yong Sheng Tan
;
Anand Sachithanandan
- Publication Type:Letter
- MeSH:
Coronary Artery Disease
- From:
The Medical Journal of Malaysia
2015;70(2):114-115
- CountryMalaysia
- Language:English
-
Abstract:
The incidence of premature multi-vessel coronary artery
disease (CAD) is on the rise in Malaysia. The pathogenesis
of coronary atherosclerosis is multi-factorial with
dyslipidaemia being one such risk factor. Elevated total
cholesterol (TC), low density lipoprotein cholesterol (LDL-C)
and triglycerides (TG) levels are primarily responsible. We
analysed the fasting pre-operative lipid profiles of coronary
artery bypass graft (CABG) patients with symptomatic
severe premature CAD. A majority of patients had an
elevated LDL cholesterol level despite being on a statin.
Similarly, no patient with an elevated TG level was
prescribed a fibrate.
Pre-operative control of known dyslipidaemia was
suboptimal in young adults with angiographially proven
severe symptomatic CAD. This is either due to
subtherapeutic dose prescribing or failure to commence
appropriate anti-lipid drugs. Collectively, general
practitioners, cardiologists and cardiac surgeons must be
more diligent in monitoring lipid profiles in such patients
and be more meticulous in prescribing therapeutic doses to
achieve target control.
- Full text:P020150724532560848952.pdf
