Ultrasonographic Findings in Eyes with Retinopathy of Prematurity in Malaysia
- Author:
Lee Kok Foo
;
Abdul Rahim Adlina
;
Raja Azmi Mohd Noor
;
Wan Hazabbah Wan Hitam
;
Embong Zunaina
;
Abdullah Sarimah
;
Noramazlan Ramli
;
Zulkifli Abdul Ghani
;
Josept Vijaya Alagaratnam
;
Jamalia Rahmat
;
Sunder Ramasamy
;
Ismail Shatriah
- Publication Type:Journal Article
- Keywords:
Retinopathy of prematurity, funduscopic signs, B-scan ultrasonographic findings
- From:
The Medical Journal of Malaysia
2013;68(1):39-43
- CountryMalaysia
- Language:English
-
Abstract:
RetCam is an excellent screening tool for the detection of
retinopathy of prematurity (ROP). However, affordability is a barrier when adopting the use of RetCam in developing
countries. We aimed to describe different stages of ROP
using ultrasonographic B-scan and to evaluate the
association between funduscopic examinations and
ultrasonographic B-scan findings in premature neonates
with ROP in Malaysia. A descriptive cross sectional study
was conducted in 90 eyes of 47 premature neonates with
different stages of ROP in three tertiary hospitals in
Malaysia. Experienced ophthalmologists performed detailed
funduscopic examinations using binocular indirect
ophthalmoscopy (BIO). A masked examiner performed a 10
MHz ultrasonographic B-scan evaluation with 12 meridian
position images within 48 hours of clinical diagnosis. Data
from the clinical examination and ultrasonographic findings
were collected and analysed. We recruited 37 eyes (41.1%)
with stage 1 ROP, 29 eyes (32.3%) with stage 2, 18 eyes
(20.0%) with stage 3, and 3 eyes (3.3%) with stages 4 and 5
based on the clinical assessment. Ultrasonography
correctly identified 3 (8.1%) stage 1 eyes, 17 (58.6%) stage 2 eyes, 13 (72.2%) stage 3 eyes, and 3 each (100%) of the stage 4 and 5 eyes. There was a significant association between the funduscopic signs and the ultrasound findings for stage
2 ROP and above (Fisher’s exact test, p <0.001). In
conclusion, all stages of ROP were detected and described
with a 10 MHz ultrasonic B-scan system. A significant
association was observed between funduscopic signs and
ultrasonographic findings in premature Malaysian neonates
with stage 2 ROP and above.