Contemporary Surgical Management of Advanced End Stage Emphysema: An Evidence Based Review
- Author:
Anand Sachithanandan
;
Balaji Badmanaban
- Publication Type:Review
- Keywords:
Emphysema, Lung volume reduction surgery, Lung transplantation
- From:
The Medical Journal of Malaysia
2012;67(3):253-258
- CountryMalaysia
- Language:English
-
Abstract:
Emphysema is a progressive unrelenting component of
chronic obstructive pulmonary disease and a major source of
mortality and morbidity globally. The prevalence of
moderate to severe emphysema is approximately 5% in
Malaysia and likely to increase in the future. Hence advanced emphysema will emerge as a leading cause of hospital admission and a major consumer of healthcare resources in this country in the future. Patients with advanced disease have a poor quality of life and reduced survival. Medical therapy has been largely ineffective for many patients however certain subgroups have disease amenable to surgical palliation. Effective surgical therapies include lung volume reduction surgery, lung transplantation and bullectomy. This article is a comprehensive evidence based review of the literature evaluating the rationale, efficacy, safety and limitations of surgery for advanced emphysema highlighting the importance of meticulous patient selection
and local factors relevant to Malaysia.
