Clinical Profile and Aetiology of Optic Neuritis in Hospital Universiti Sains Malaysia – 5 Years Review
- Author:
Ismail Shatriah
;
Wan Hazabbah Wan Hitam
;
Muhd-Nor Nor-Idahriani
;
Daud Jakiyah
;
Embong Zunaina
- Publication Type:Journal Article
- Keywords:
Optic neuritis, Malay
- From:
The Medical Journal of Malaysia
2012;67(2):159-164
- CountryMalaysia
- Language:English
-
Abstract:
Although few studies concerning optic neuritis (ON) in Asian countries have been reported, there is no report about ON in Malaysia particularly within the Malay population. We aimed
to determine the clinical manifestation, visual outcome and
aetiology of ON in Malays, and discussed the literature of ON studies in other Asian populations. This was a retrospective study involving 31 consecutive patients (41 eyes) with ON treated at Hospital Universiti Sains Malaysia commencing from July 2005 till January 2010 with a period of follow-up ranging from 18-60 months. The clinical features, laboratory
results, possible aetiology, and visual acuity after one year were analysed. Females were the predominant group. The
age of the patients ranged between 3-55 years and peaked
between 21-30 years old. 67.7% of the patients had
unilateral involvement. Pain on ocular movement was
observed in 31.7% of the affected eyes. 73.3% of 41 involved eyes showed visual acuity equal 6/60 or worse on
presentation. Paracentral scotoma was the most common
visual field defect noted. Optic disc papillitis proved more widespread compared to the retrobulbar type of ON. The
aetiology was idiopathic in more than 50%, while the risk of multiple sclerosis was extremely low (3.2%) in our series. 66.0% demonstrating visual acuity improved to 6/12 or better at one year after the attack. 16.1% showed evidence of recurrence during follow-up. In conclusion, the clinical profile and aetiology of ON in Malay patients are comparable to other ON studies reported by other Asian countries.
