Multiple metastatic renal cell carcinoma isolated to pancreas
- Author:
Cem Comunoglu
;
Gulum Altaca
;
Ebru Demiralay
;
Gokhan Moray
- Publication Type:Case Reports
- Keywords:
pancreatic metastasis, renal cell carcinoma, pancreatic resection.
- From:The Malaysian Journal of Pathology
2012;34(1):63-66
- CountryMalaysia
- Language:English
-
Abstract:
Renal cell carcinoma (RCC) metastases to the pancreas are reported to be rare. Isolated multiple
pancreatic metastases are even rarer. We report a 68-year-old asymptomatic male patient who
presented with multiple metastatic nodular lesions in the pancreas demonstrated by computerized
tomography 3.5 years after radical nephrectomy performed for clear cell RCC. Spleen-preserving
total pancreatectomy was performed. Gross examination revealed fi ve well-demarcated tumoral
nodules in the head, body and tail of the pancreas. Histopathological examination revealed clusters
of epithelial clear cells, immunohistochemically positive for CD10 and vimentin, and negative for
CK19 and chromogranin, supporting a diagnosis of metastatic RCC. The patient has remained well
at 29 months post-resection, in agreement with recent experience that radical resection for multiple
isolated metastatic nodular lesions can achieve improved survival and better quality of life.
- Full text:W020151218428211384946.pdf
