Insecticide resistance development in Aedes aegypti upon selection pressure with malathion
- Author:
Hidayati, H.*
;
Nazni, W.A.
;
Lee, H.L.
;
Sofian-Azirun, M.
- Publication Type:Journal Article
- From:Tropical Biomedicine
2011;28(2):425-437
- CountryMalaysia
- Language:English
-
Abstract:
Bioassay test against malathion had been carried out with larval and adult stages
of Aedes aegypti. The mosquitoes were under selection pressure against malathion for fortyfive
consecutive generations. The rate of resistance development was measured by LC50 and
LT50 values. The larvae and adult females, after subjection to malathion selection for 45
generations, developed high resistance level to malathion, with resistance ratio of 52.7 and
3.24 folds, respectively over control mosquitoes. Cross-resistance towards the same and
different groups of insecticides was determined using the F44 and F45 malathion-selected
adult females. Insecticides tested were DDT (4.0%), permethrin (0.75%), propoxur (0.1%),
fenitrothion (1%), λ-cyhalothrin (0.05%) and cyfluthrin (0.15%). Results indicated that the
mosquitoes were highly resistant to DDT and fenitrothion, moderately resistant to propoxur,
tolerant to permethrin and λ-cyhalothrin, and very low resistant to cyfluthrin.
- Full text:W020150615379360120858.pdf
